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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human C6 HGNC:1339 (HGNC)
729 (Entrez Gene)
217050 (OMIM)
Complement component 6 (MyGene.info)
HGNC homology
Chr5 p13.1 Chr5:41142116-41261486 (-)
complement component 6 deficiency
P13671 (UniProt | EBI)
NM_000065 (RefSeq)
mouse C6 MGI:88233 (MGI)
12274 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 1.97 cM Chr15:4727067-4804045 (+)
12274 (NCBI Gene Model)
NP_057913 (RefSeq)
NM_016704 (RefSeq)
rat C6 24237 (Entrez Gene)
Chr2 q16 Q811M5 (UniProt | EBI)
NM_176074 (RefSeq)
chimpanzee C6 449612 (Entrez Gene)
Chr5 P61134 (UniProt | EBI)
NM_001009015 (RefSeq)
cattle C6 507749 (Entrez Gene)
Chr20 Q29RU4 (UniProt | EBI)
NM_001045979 (RefSeq)
dog C6 479348 (Entrez Gene)
Chr4 XP_022273590 (RefSeq)
chicken C6 431585 (Entrez Gene)
ChrZ NP_001138321 (RefSeq)
NM_001144849 (RefSeq)
zebrafish c6 393611 (Entrez Gene)
Chr21 NP_956932 (RefSeq)
NM_200638 (RefSeq)
frog, western clawed c6.1 100485342 (Entrez Gene)
Chr1 XP_002940164 (RefSeq)
c6.2 448630 (Entrez Gene)
Chr1 NP_001006864 (RefSeq)
NM_001006863 (RefSeq)
macaque, rhesus C6 696266 (Entrez Gene)
Chr6 XP_014995439 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory