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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NPC2 HGNC:14537 (HGNC)
10577 (Entrez Gene)
601015 (OMIM)
HGNC homology
Chr14 q24.3 Chr14:74479940-74493475 (-)
Niemann-Pick disease type C2
P61916 (UniProt | EBI)
NM_006432 (RefSeq)
mouse Npc2 MGI:1915213 (MGI)
67963 (Entrez Gene)
Gene Tree
HGNC homology
Chr12 39.37 cM Chr12:84754559-84773112 (-)
Niemann-Pick disease
67963 (NCBI Gene Model)
Q9Z0J0 (UniProt | EBI)
NM_023409 (RefSeq)
rat Npc2 286898 (Entrez Gene)
Chr6 q31 NP_775141 (RefSeq)
NM_173118 (RefSeq)
chimpanzee NPC2 450192 (Entrez Gene)
Chr14 P61917 (UniProt | EBI)
NM_001009075 (RefSeq)
cattle NPC2 280815 (Entrez Gene)
Chr10 P79345 (UniProt | EBI)
NM_173918 (RefSeq)
dog NPC2 403920 (Entrez Gene)
Chr8 Q28895 (UniProt | EBI)
NM_001003242 (RefSeq)
chicken NPC2 423353 (Entrez Gene)
Chr5 NP_001026374 (RefSeq)
NM_001031203 (RefSeq)
zebrafish npc2 282673 (Entrez Gene)
Chr17 Q9DGJ3 (UniProt | EBI)
NM_173224 (RefSeq)
zgc:193725 565099 (Entrez Gene)
Chr17 NP_001122191 (RefSeq)
NM_001128719 (RefSeq)
frog, western clawed npc2 493351 (Entrez Gene)
Chr8 NP_001007988 (RefSeq)
NM_001007987 (RefSeq)
macaque, rhesus NPC2 699881 (Entrez Gene)
Chr7 NP_001253689 (RefSeq)
NM_001266760 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory