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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPTLC1 HGNC:11277 (HGNC)
10558 (Entrez Gene)
605712 (OMIM)
SPTLC1 (MyGene.info)
HGNC homology
Chr9 q22.31 Chr9:92031134-92115474 (-)
hereditary sensory and autonomic neuropathy type 1A
O15269 (UniProt | EBI)
NM_001281303 (RefSeq)
mouse Sptlc1 MGI:1099431 (MGI)
268656 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 27.68 cM Chr13:53332748-53377397 (-)
ENSMUSG00000021468 (Ensembl Gene Model)
ENSMUSP00000021920 (Ensembl)
ENSMUST00000021920 (Ensembl)
rat Sptlc1 361213 (Entrez Gene)
Chr17 p14 D4A2H2 (UniProt | EBI)
NM_001108406 (RefSeq)
chimpanzee SPTLC1 464590 (Entrez Gene)
Chr9 NP_001267361 (RefSeq)
NM_001280432 (RefSeq)
cattle SPTLC1 614165 (Entrez Gene)
Chr8 Q3MHG1 (UniProt | EBI)
NM_001034749 (RefSeq)
dog SPTLC1 484192 (Entrez Gene)
Chr1 XP_005616008 (RefSeq)
chicken SPTLC1 426145 (Entrez Gene)
ChrZ XP_004949309 (RefSeq)
zebrafish sptlc1 553981 (Entrez Gene)
Chr10 NP_001018307 (RefSeq)
NM_001020471 (RefSeq)
frog, western clawed sptlc1 779626 (Entrez Gene)
Chr1 NP_001073042 (RefSeq)
NM_001079574 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory