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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
468

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GDF5 HGNC:4220 (HGNC)
8200 (Entrez Gene)
601146 (OMIM)
Chr20 q11.2 Chr20:35433351-35438247 (-)
GRCh38
Acromesomelic Dysplasia, Hunter-Thompson Type
Brachydactyly, Type A1, C; BDA1C
Brachydactyly, Type A2; BDA2
Brachydactyly, Type C; BDC
Chondrodysplasia, Grebe Type
Fibular Hypoplasia and Complex Brachydactyly
Multiple Synostoses Syndrome 2; SYNS2
Osteoarthritis Susceptibility 5; OS5
Symphalangism, Proximal, 1B; SYM1B
P43026 (UniProt | EBI)
NM_000557 (RefSeq)
mouse Gdf5 MGI:95688 (MGI)
14563 (Entrez Gene)
Gene Tree
VISTA-Point
Chr2 77.26 cM Chr2:155941023-155945367 (-)
GRCm38
Acromesomelic Dysplasia, Hunter-Thompson Type
Brachydactyly, Type A1, C; BDA1C
Brachydactyly, Type A2; BDA2
Brachydactyly, Type C; BDC
Chondrodysplasia, Grebe Type
Fibular Hypoplasia and Complex Brachydactyly
Multiple Synostoses Syndrome 2; SYNS2
Osteoarthritis Susceptibility 1; OS1
OTTMUSG00000015989 (VEGA)
OTTMUSP00000017076 (VEGA)
OTTMUST00000038081 (VEGA)
rat Gdf5 252835 (Entrez Gene)
Chr3 XP_001066344 (RefSeq)
chimpanzee GDF5 458202 (Entrez Gene)
Chr20 XP_530287 (RefSeq)
rhesus macaque GDF5 705432 (Entrez Gene)
Chr10 XP_001099806 (RefSeq)
cattle GDF5 539559 (Entrez Gene)
Chr13 NP_001179202 (RefSeq)
NM_001192273 (RefSeq)
dog GDF5 485850 (Entrez Gene)
Chr24 XP_542974 (RefSeq)
chicken GDF5 374249 (Entrez Gene)
Chr20 NP_989669 (RefSeq)
NM_204338 (RefSeq)
western clawed frog gdf5 100189547 (Entrez Gene)
ChrUN NP_001128589 (RefSeq)
NM_001135117 (RefSeq)
zebrafish gdf5 100334210 (Entrez Gene)
Chr6 XP_002662587 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory