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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TSC2 HGNC:12363 (HGNC)
7249 (Entrez Gene)
191092 (OMIM)
TSC2 (MyGene.info)
HGNC homology
Chr16 p13.3 Chr16:2047804-2088720 (+)
tuberous sclerosis
P49815 (UniProt | EBI)
NM_001318832 (RefSeq)
mouse Tsc2 MGI:102548 (MGI)
22084 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 12.41 cM Chr17:24595816-24632627 (-)
autistic disorder
tuberous sclerosis
uterine fibroid
22084 (NCBI Gene Model)
Q61037 (UniProt | EBI)
NM_001286720 (RefSeq)
rat Tsc2 24855 (Entrez Gene)
Chr10 q12 P49816 (UniProt | EBI)
NM_012680 (RefSeq)
chimpanzee TSC2 468086 (Entrez Gene)
Chr16 XP_024205808 (RefSeq)
cattle TSC2 504985 (Entrez Gene)
Chr25 XP_024841203 (RefSeq)
dog TSC2 479883 (Entrez Gene)
Chr6 XP_005621774 (RefSeq)
chicken TSC2 416552 (Entrez Gene)
Chr14 XP_015149933 (RefSeq)
zebrafish tsc2 567524 (Entrez Gene)
Chr1 NP_001315330 (RefSeq)
NM_001328401 (RefSeq)
frog, western clawed tsc2 100170546 (Entrez Gene)
Chr9 NP_001123795 (RefSeq)
NM_001130323 (RefSeq)
macaque, rhesus TSC2 694965 (Entrez Gene)
Chr20 XP_014980837 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory