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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TSC2 HGNC:12363 (HGNC)
7249 (Entrez Gene)
Chr16 p13.3 Chr16:2047802-2088712 (+)
Lymphangioleiomyomatosis; LAM
Tuberous Sclerosis 2; TSC2
P49815 (UniProt | EBI)
NM_000548 (RefSeq)
mouse Tsc2 MGI:102548 (MGI)
22084 (Entrez Gene)
Gene Tree
Chr17 12.41 cM Chr17:24595937-24632629 (-)
Tuberous Sclerosis 2; TSC2
ENSMUSG00000002496 (Ensembl Gene Model)
ENSMUSP00000094986 (Ensembl)
ENSMUST00000097373 (Ensembl)
rat Tsc2 24855 (Entrez Gene)
Chr10 q12 P49816 (UniProt | EBI)
NM_012680 (RefSeq)
chimpanzee TSC2 468086 (Entrez Gene)
Chr16 XP_523477 (RefSeq)
rhesus macaque TSC2 694965 (Entrez Gene)
Chr20 XP_001083027 (RefSeq)
cattle TSC2 504985 (Entrez Gene)
Chr25 XP_003584053 (RefSeq)
dog TSC2 479883 (Entrez Gene)
Chr6 XP_537008 (RefSeq)
chicken TSC2 416552 (Entrez Gene)
Chr14 XP_003642168 (RefSeq)
western clawed frog tsc2 100170546 (Entrez Gene)
ChrUN NP_001123795 (RefSeq)
NM_001130323 (RefSeq)
zebrafish tsc2 567524 (Entrez Gene)
Chr1 XP_009293248 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory