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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TP53 HGNC:11998 (HGNC)
7157 (Entrez Gene)
191170 (OMIM)
P53 (MyGene.info)
HGNC homology
Chr17 p13.1 Chr17:7668402-7687550 (-)
adrenocortical carcinoma
basal cell carcinoma
breast cancer
choroid plexus papilloma
colorectal cancer
hepatocellular carcinoma
Li-Fraumeni syndrome
nasopharynx carcinoma
pancreatic carcinoma
P04637 (UniProt | EBI)
NM_001126114 (RefSeq)
mouse Trp53 MGI:98834 (MGI)
22059 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 42.83 cM Chr11:69580359-69591873 (+)
breast cancer
CHARGE syndrome
diffuse large B-cell lymphoma
dyskeratosis congenita
endometrial cancer
glioblastoma multiforme
Li-Fraumeni syndrome
OTTMUSG00000005982 (VEGA)
OTTMUSP00000006194 (VEGA)
OTTMUST00000013379 (VEGA)
rat Tp53 24842 (Entrez Gene)
Chr10 q24 P10361 (UniProt | EBI)
NM_030989 (RefSeq)
chimpanzee TP53 455214 (Entrez Gene)
Chr17 XP_001172077 (RefSeq)
cattle TP53 281542 (Entrez Gene)
Chr19 q15 P67939 (UniProt | EBI)
NM_174201 (RefSeq)
dog TP53 403869 (Entrez Gene)
Chr5 Q29537 (UniProt | EBI)
NM_001003210 (RefSeq)
zebrafish tp53 30590 (Entrez Gene)
Chr5 P79734 (UniProt | EBI)
NM_131327 (RefSeq)
frog, western clawed tp53 431679 (Entrez Gene)
ChrUN NP_001001903 (RefSeq)
NM_001001903 (RefSeq)
macaque, rhesus TP53 716170 (Entrez Gene)
Chr16 P56424 (UniProt | EBI)
NM_001047151 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory