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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SMC1A HGNC:11111 (HGNC)
8243 (Entrez Gene)
300040 (OMIM)
HGNC homology
ChrX p11.22-p11.21 ChrX:53374149-53422728 (-)
Cornelia De Lange Syndrome 2; CDLS2
Q14683 (UniProt | EBI)
NM_001281463 (RefSeq)
mouse Smc1a MGI:1344345 (MGI)
24061 (Entrez Gene)
Gene Tree
HGNC homology
ChrX 68.46 cM ChrX:152016428-152062694 (+)
OTTMUSG00000019685 (VEGA)
OTTMUSP00000021286 (VEGA)
OTTMUST00000047121 (VEGA)
rat Smc1a 63996 (Entrez Gene)
ChrX q21.3 Q9Z1M9 (UniProt | EBI)
NM_031683 (RefSeq)
chimpanzee SMC1A 473619 (Entrez Gene)
ChrX XP_009437399 (RefSeq)
rhesus macaque SMC1A 677711 (Entrez Gene)
ChrX XP_001091228 (RefSeq)
cattle SMC1A 282370 (Entrez Gene)
ChrX O97593 (UniProt | EBI)
NM_174614 (RefSeq)
dog SMC1A 480928 (Entrez Gene)
ChrX XP_538049 (RefSeq)
chicken SMC1A 395187 (Entrez Gene)
ChrUN NP_989847 (RefSeq)
NM_204516 (RefSeq)
western clawed frog smc1a 100493711 (Entrez Gene)
ChrUN XP_002935560 (RefSeq)
zebrafish smc1a 559665 (Entrez Gene)
Chr23 NP_001155103 (RefSeq)
NM_001161631 (RefSeq)
smc1al 403060 (Entrez Gene)
Chr23 NP_997975 (RefSeq)
NM_212810 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory