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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
459

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HNF1A HGNC:11621 (HGNC)
6927 (Entrez Gene)
142410 (OMIM)
Chr12 q24.2 Chr12:120978058-121002512 (+)
GRCh38
Diabetes Mellitus, Insulin-Dependent, 20; IDDM20
Diabetes Mellitus, Insulin-Dependent; IDDM
Diabetes Mellitus, Noninsulin-Dependent; NIDDM
Hepatic Adenomas, Familial
Maturity-Onset Diabetes of the Young, Type 3; MODY3
Renal Cell Carcinoma, Nonpapillary; RCC
P20823 (UniProt | EBI)
NM_000545 (RefSeq)
mouse Hnf1a MGI:98504 (MGI)
21405 (Entrez Gene)
Gene Tree
VISTA-Point
Chr5 55.99 cM Chr5:114948980-114971094 (-)
GRCm38
Diabetes Mellitus, Noninsulin-Dependent; NIDDM
Growth Hormone Insensitivity with Immunodeficiency
Maturity-Onset Diabetes of the Young, Type 3; MODY3
Phenylketonuria; PKU
OTTMUSG00000014612 (VEGA)
OTTMUSP00000015521 (VEGA)
OTTMUST00000034659 (VEGA)
rat Hnf1a 24817 (Entrez Gene)
Chr12 q16 P15257 (UniProt | EBI)
NM_012669 (RefSeq)
chimpanzee LOC744121 744121 (Entrez Gene)
Chr12 XP_001148554 (RefSeq)
rhesus macaque LOC701243 701243 (Entrez Gene)
Chr11 XP_001089567 (RefSeq)
cattle HNF1A 503578 (Entrez Gene)
Chr17 NP_001179453 (RefSeq)
NM_001192524 (RefSeq)
dog HNF1A 486303 (Entrez Gene)
Chr26 XP_543429 (RefSeq)
chicken HNF1A 416967 (Entrez Gene)
Chr15 Q90867 (UniProt | EBI)
NM_001030668 (RefSeq)
western clawed frog hnf1a 100144688 (Entrez Gene)
ChrUN NP_001116920 (RefSeq)
NM_001123448 (RefSeq)
zebrafish hnf1a 266961 (Entrez Gene)
Chr8 NP_739570 (RefSeq)
NM_170764 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory