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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SMPD1 HGNC:11120 (HGNC)
6609 (Entrez Gene)
607608 (OMIM)
HGNC homology
Chr11 p15.4 Chr11:6390301-6394998 (+)
Niemann-Pick disease type A
Niemann-Pick disease type B
P17405 (UniProt | EBI)
NM_001318088 (RefSeq)
mouse Smpd1 MGI:98325 (MGI)
20597 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 55.9 cM Chr7:105554360-105558389 (+)
Niemann-Pick disease
OTTMUSG00000060466 (VEGA)
OTTMUSP00000076958 (VEGA)
OTTMUST00000147939 (VEGA)
rat Smpd1 308909 (Entrez Gene)
Chr1 q32 NP_001006998 (RefSeq)
NM_001006997 (RefSeq)
chimpanzee SMPD1 450990 (Entrez Gene)
Chr11 XP_508253 (RefSeq)
cattle SMPD1 505097 (Entrez Gene)
Chr15 Q0VD19 (UniProt | EBI)
NM_001075187 (RefSeq)
dog SMPD1 485334 (Entrez Gene)
Chr21 XP_542452 (RefSeq)
chicken SMPD1 419077 (Entrez Gene)
Chr1 XP_015136421 (RefSeq)
zebrafish smpd1 556700 (Entrez Gene)
Chr10 NP_001313465 (RefSeq)
NM_001326536 (RefSeq)
frog, western clawed smpd1 100487433 (Entrez Gene)
ChrUN XP_002943546 (RefSeq)
macaque, rhesus SMPD1 711248 (Entrez Gene)
Chr14 XP_001110212 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory