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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human POLE HGNC:9177 (HGNC)
5426 (Entrez Gene)
174762 (OMIM)
POLE (enzyme) (MyGene.info)
HGNC homology
Chr12 q24.33 Chr12:132623762-132687524 (-)
colorectal cancer
Q07864 (UniProt | EBI)
NM_006231 (RefSeq)
mouse Pole MGI:1196391 (MGI)
18973 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 53.45 cM Chr5:110286319-110337468 (+)
18973 (NCBI Gene Model)
Q9WVF7 (UniProt | EBI)
NM_011132 (RefSeq)
rat Pole 304573 (Entrez Gene)
Chr12 q16 NP_001100622 (RefSeq)
NM_001107152 (RefSeq)
chimpanzee POLE 467165 (Entrez Gene)
Chr12 XP_016780169 (RefSeq)
cattle POLE 785457 (Entrez Gene)
Chr17 NP_001178358 (RefSeq)
NM_001191429 (RefSeq)
dog POLE 486223 (Entrez Gene)
Chr26 XP_022265956 (RefSeq)
chicken POLE 416997 (Entrez Gene)
Chr15 XP_001233985 (RefSeq)
NM_001012530 (RefSeq)
zebrafish pole 553405 (Entrez Gene)
Chr5 NP_001121995 (RefSeq)
NM_001128523 (RefSeq)
frog, western clawed pole 100498309 (Entrez Gene)
Chr1 XP_004910692 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory