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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human POLE HGNC:9177 (HGNC)
5426 (Entrez Gene)
174762 (OMIM)
HGNC homology
Chr12 q24.3 Chr12:132623762-132687524 (-)
Colorectal Cancer, Susceptibility to, 12; CRCS12
Facial Dysmorphism, Immunodeficiency, Livedo, and Short Stature; FILS
Q07864 (UniProt | EBI)
NM_006231 (RefSeq)
mouse Pole MGI:1196391 (MGI)
18973 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 53.45 cM Chr5:110286306-110337474 (+)
OTTMUSG00000026219 (VEGA)
OTTMUSP00000032240 (VEGA)
OTTMUST00000064842 (VEGA)
rat Pole 304573 (Entrez Gene)
Chr12 q16 NP_001100622 (RefSeq)
NM_001107152 (RefSeq)
chimpanzee LOC467165 467165 (Entrez Gene)
Chr12 XP_009424889 (RefSeq)
cattle POLE 785457 (Entrez Gene)
Chr17 NP_001178358 (RefSeq)
NM_001191429 (RefSeq)
dog POLE 486223 (Entrez Gene)
Chr26 XP_543348 (RefSeq)
chicken POLE 416997 (Entrez Gene)
Chr15 XP_001233985 (RefSeq)
NM_001012530 (RefSeq)
western clawed frog pole 100498309 (Entrez Gene)
ChrUN XP_004910692 (RefSeq)
zebrafish pole 553405 (Entrez Gene)
Chr5 NP_001121995 (RefSeq)
NM_001128523 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory