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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human C2 HGNC:1248 (HGNC)
717 (Entrez Gene)
613927 (OMIM)
Complement component 2 (MyGene.info)
HGNC homology
Chr6 p21.33 Chr6:31897785-31945674 (+)
age related macular degeneration 14
complement component 2 deficiency
P06681 (UniProt | EBI)
NM_001282457 (RefSeq)
mouse C2 MGI:88226 (MGI)
12263 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 18.41 cM Chr17:34862602-34882100 (-)
12263 (NCBI Gene Model)
P21180 (UniProt | EBI)
NM_013484 (RefSeq)
rat C2 24231 (Entrez Gene)
Chr20 p12 NP_757376 (RefSeq)
NM_172222 (RefSeq)
chimpanzee C2 100608992 (Entrez Gene)
Chr6 Q8SQ74 (UniProt | EBI)
cattle C2 515440 (Entrez Gene)
Chr23 Q3SYW2 (UniProt | EBI)
NM_001034492 (RefSeq)
dog C2 474853 (Entrez Gene)
Chr12 XP_013973817 (RefSeq)
chicken C2 419574 (Entrez Gene)
Chr23 XP_417722 (RefSeq)
zebrafish si:ch1073-280e3.1 563828 (Entrez Gene)
Chr15 XP_009289626 (RefSeq)
frog, western clawed c2 100491079 (Entrez Gene)
Chr8 XP_002943019 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory