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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
45

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human C2 HGNC:1248 (HGNC)
717 (Entrez Gene)
613927 (OMIM)
Chr6 p21.3 Chr6:31897785-31945674 (+)
GRCh38
Complement Component 2 Deficiency; C2D
Macular Degeneration, Age-Related, 14; ARMD14
P06681 (UniProt | EBI)
NM_000063 (RefSeq)
mouse C2 MGI:88226 (MGI)
12263 (Entrez Gene)
Gene Tree
VISTA-Point
Chr17 18.41 cM Chr17:34862604-34898265 (-)
GRCm38
OTTMUSG00000034003 (VEGA)
OTTMUSP00000046411 (VEGA)
OTTMUST00000085830 (VEGA)
rat C2 24231 (Entrez Gene)
Chr20 p12 NP_757376 (RefSeq)
NM_172222 (RefSeq)
chimpanzee C2 100608992 (Entrez Gene)
Chr6 XP_003311224 (RefSeq)
cattle C2 515440 (Entrez Gene)
Chr23 Q3SYW2 (UniProt | EBI)
NM_001034492 (RefSeq)
dog C2 474853 (Entrez Gene)
Chr12 XP_860410 (RefSeq)
chicken C2 419574 (Entrez Gene)
Chr23 XP_417722 (RefSeq)
western clawed frog c2 100491079 (Entrez Gene)
ChrUN XP_002943019 (RefSeq)
zebrafish LOC563828 563828 (Entrez Gene)
Chr15 XP_001921532 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory