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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KNL1 HGNC:24054 (HGNC)
57082 (Entrez Gene)
609173 (OMIM)
CASC5 (MyGene.info)
HGNC homology
Chr15 q15.1 Chr15:40594012-40664342 (+)
primary autosomal recessive microcephaly 4
Q8NG31 (UniProt | EBI)
NM_170589 (RefSeq)
mouse Knl1 MGI:1923714 (MGI)
76464 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 59.85 cM Chr2:119047038-119104829 (+)
76464 (NCBI Gene Model)
Q66JQ7 (UniProt | EBI)
NM_029617 (RefSeq)
rat Knl1 311327 (Entrez Gene)
Chr3 q35 NP_001164065 (RefSeq)
NM_001170594 (RefSeq)
chimpanzee KNL1 453338 (Entrez Gene)
Chr15 XP_016783437 (RefSeq)
cattle KNL1 787969 (Entrez Gene)
Chr10 XP_002690867 (RefSeq)
dog KNL1 478260 (Entrez Gene)
Chr30 XP_005638313 (RefSeq)
chicken KNL1 423007 (Entrez Gene)
Chr5 XP_004941355 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory