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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PLP1 HGNC:9086 (HGNC)
5354 (Entrez Gene)
300401 (OMIM)
HGNC homology
ChrX q22 ChrX:103776506-103792619 (+)
Pelizaeus-Merzbacher Disease; PMD
Spastic Paraplegia 2, X-Linked; SPG2
P60201 (UniProt | EBI)
NM_000533 (RefSeq)
mouse Plp1 MGI:97623 (MGI)
18823 (Entrez Gene)
Gene Tree
ChrX 59.1 cM ChrX:136822671-136839733 (+)
Pelizaeus-Merzbacher Disease; PMD
Spastic Paraplegia 2, X-Linked; SPG2
OTTMUSG00000016519 (VEGA)
OTTMUSP00000017800 (VEGA)
OTTMUST00000039923 (VEGA)
rat Plp1 24943 (Entrez Gene)
ChrX q35 P60203 (UniProt | EBI)
NM_030990 (RefSeq)
chimpanzee PLP1 465785 (Entrez Gene)
ChrX XP_001141683 (RefSeq)
rhesus macaque PLP1 697887 (Entrez Gene)
ChrX NP_001247468 (RefSeq)
NM_001260539 (RefSeq)
cattle PLP1 281410 (Entrez Gene)
ChrX Xq21 P04116 (UniProt | EBI)
NM_174149 (RefSeq)
dog PLP1 481002 (Entrez Gene)
ChrX P23294 (UniProt | EBI)
NM_001013834 (RefSeq)
chicken PLP1 396214 (Entrez Gene)
Chr4 P23289 (UniProt | EBI)
NM_205277 (RefSeq)
western clawed frog plp1 613099 (Entrez Gene)
ChrUN NP_001027507 (RefSeq)
NM_001032336 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory