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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IRF6 HGNC:6121 (HGNC)
3664 (Entrez Gene)
607199 (OMIM)
IRF6 (MyGene.info)
HGNC homology
Chr1 q32.2 Chr1:209785623-209806175 (-)
orofacial cleft
popliteal pterygium syndrome
Van der Woude syndrome
O14896 (UniProt | EBI)
NM_006147 (RefSeq)
mouse Irf6 MGI:1859211 (MGI)
54139 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 97.6 cM Chr1:193153111-193172023 (+)
popliteal pterygium syndrome
Van der Woude syndrome
OTTMUSG00000033402 (VEGA)
OTTMUSP00000045120 (VEGA)
OTTMUST00000083863 (VEGA)
rat Irf6 364081 (Entrez Gene)
Chr13 q27 NP_001102329 (RefSeq)
NM_001108859 (RefSeq)
chimpanzee IRF6 457701 (Entrez Gene)
Chr1 XP_514168 (RefSeq)
cattle IRF6 614253 (Entrez Gene)
Chr16 Q08DD6 (UniProt | EBI)
NM_001076934 (RefSeq)
dog IRF6 480015 (Entrez Gene)
Chr7 XP_537138 (RefSeq)
chicken IRF6 419863 (Entrez Gene)
Chr26 XP_015154525 (RefSeq)
zebrafish irf6 393570 (Entrez Gene)
Chr22 NP_956892 (RefSeq)
NM_200598 (RefSeq)
frog, western clawed irf6 594908 (Entrez Gene)
Chr5 NP_001025493 (RefSeq)
NM_001030322 (RefSeq)
macaque, rhesus IRF6 712958 (Entrez Gene)
Chr1 NP_001253947 (RefSeq)
NM_001267018 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory