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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human YAP1 HGNC:16262 (HGNC)
10413 (Entrez Gene)
606608 (OMIM)
HGNC homology
Chr11 q13 Chr11:102110254-102233423 (+)
Coloboma, Ocular, with or without Hearing Impairment, Cleft Lip/Palate, and/or Mental Retardation; COB1
P46937 (UniProt | EBI)
NM_001195044 (RefSeq)
mouse Yap1 MGI:103262 (MGI)
22601 (Entrez Gene)
Gene Tree
Chr9 2.46 cM Chr9:7931999-8004596 (-)
OTTMUSG00000038037 (VEGA)
OTTMUSP00000054974 (VEGA)
OTTMUST00000097973 (VEGA)
chimpanzee YAP1 451506 (Entrez Gene)
Chr11 XP_001151467 (RefSeq)
rhesus macaque YAP1 704382 (Entrez Gene)
Chr14 XP_002799820 (RefSeq)
cattle YAP1 100336629 (Entrez Gene)
Chr15 XP_015330075 (RefSeq)
dog YAP1 479465 (Entrez Gene)
Chr5 XP_536601 (RefSeq)
chicken YAP1 396171 (Entrez Gene)
Chr1 P46936 (UniProt | EBI)
NM_205243 (RefSeq)
western clawed frog yap1 100488779 (Entrez Gene)
ChrUN NP_001182697 (RefSeq)
NM_001195768 (RefSeq)
zebrafish yap1 561411 (Entrez Gene)
Chr18 Q1L8J7 (UniProt | EBI)
NM_001139480 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory