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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RAPGEF4 HGNC:16626 (HGNC)
11069 (Entrez Gene)
606058 (OMIM)
RAPGEF4 (MyGene.info)
HGNC homology
Chr2 q31.1 Chr2:172735282-173052893 (+)
Q8WZA2 (UniProt | EBI)
NM_007023 (RefSeq)
mouse Rapgef4 MGI:1917723 (MGI)
56508 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 42.9 cM Chr2:71981240-72257474 (+)
ENSMUSG00000049044 (Ensembl Gene Model)
ENSMUSP00000088336 (Ensembl)
ENSMUST00000090826 (Ensembl)
rat Rapgef4 252857 (Entrez Gene)
Chr3 q23 Q9Z1C7 (UniProt | EBI)
chimpanzee RAPGEF4 459744 (Entrez Gene)
Chr2B XP_016805536 (RefSeq)
cattle RAPGEF4 537312 (Entrez Gene)
Chr2 NP_001179831 (RefSeq)
NM_001192902 (RefSeq)
dog RAPGEF4 488402 (Entrez Gene)
Chr36 XP_013966163 (RefSeq)
chicken RAPGEF4 429022 (Entrez Gene)
Chr7 XP_025008351 (RefSeq)
zebrafish rapgef4 559170 (Entrez Gene)
Chr9 XP_021334493 (RefSeq)
frog, western clawed rapgef4 100497690 (Entrez Gene)
Chr9 XP_004917772 (RefSeq)
macaque, rhesus RAPGEF4 698148 (Entrez Gene)
Chr12 XP_014965867 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory