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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MPZ HGNC:7225 (HGNC)
4359 (Entrez Gene)
159440 (OMIM)
Chr1 q23.3 Chr1:161304735-161309972 (-)
Charcot-Marie-Tooth Disease, Axonal, Type 2I; CMT2I
Charcot-Marie-Tooth Disease, Axonal, Type 2J; CMT2J
Charcot-Marie-Tooth Disease, Demyelinating, Type 1B; CMT1B
Charcot-Marie-Tooth Disease, Dominant Intermediate D; CMTDID
Hypertrophic Neuropathy of Dejerine-Sottas
Neuropathy, Congenital Hypomyelinating or Amyelinating, Autosomal Recessive; CHN
Roussy-Levy Hereditary Areflexic Dystasia
P25189 (UniProt | EBI)
NM_000530 (RefSeq)
mouse Mpz MGI:103177 (MGI)
17528 (Entrez Gene)
Gene Tree
Chr1 79.05 cM Chr1:171150711-171161130 (+)
Charcot-Marie-Tooth Disease, Demyelinating, Type 1B; CMT1B
Hypertrophic Neuropathy of Dejerine-Sottas
Peripheral Demyelinating Neuropathy, Central Dysmyelination, Waardenburg Syndrome, and Hirschsprung Disease; PCWH
OTTMUSG00000021546 (VEGA)
OTTMUSP00000023997 (VEGA)
OTTMUST00000051092 (VEGA)
rat Mpz 24564 (Entrez Gene)
Chr13 q24-q25 P06907 (UniProt | EBI)
NM_017027 (RefSeq)
chimpanzee MPZ 747431 (Entrez Gene)
Chr1 XP_001173975 (RefSeq)
rhesus macaque LOC719969 719969 (Entrez Gene)
Chr1 XP_001118030 (RefSeq)
cattle MPZ 539462 (Entrez Gene)
Chr3 P10522 (UniProt | EBI)
NM_001079507 (RefSeq)
dog MPZ 488654 (Entrez Gene)
Chr38 XP_545771 (RefSeq)
chicken LOC100859605 100859605 (Entrez Gene)
ChrUN XP_003643863 (RefSeq)
western clawed frog mpz 780198 (Entrez Gene)
ChrUN A0JM41 (UniProt | EBI)
NM_001079273 (RefSeq)
zebrafish mpz 114417 (Entrez Gene)
Chr2 NP_919342 (RefSeq)
NM_194361 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.20
The Jackson Laboratory