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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MPZ HGNC:7225 (HGNC)
4359 (Entrez Gene)
159440 (OMIM)
Myelin protein zero (MyGene.info)
HGNC homology
Chr1 q23.3 Chr1:161303593-161309972 (-)
Charcot-Marie-Tooth disease dominant intermediate D
Charcot-Marie-Tooth disease type 1B
Charcot-Marie-Tooth disease type 2I
Charcot-Marie-Tooth disease type 2J
Charcot-Marie-Tooth disease type 3
Charcot-Marie-Tooth disease type 4E
P25189 (UniProt | EBI)
NM_001315491 (RefSeq)
mouse Mpz MGI:103177 (MGI)
17528 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 79.05 cM Chr1:171150711-171161130 (+)
Charcot-Marie-Tooth disease type 1B
Charcot-Marie-Tooth disease type 3
Charcot-Marie-Tooth disease type 4E
PCWH syndrome
OTTMUSG00000021546 (VEGA)
OTTMUSP00000023997 (VEGA)
OTTMUST00000051092 (VEGA)
rat Mpz 24564 (Entrez Gene)
Chr13 q24 P06907 (UniProt | EBI)
NM_017027 (RefSeq)
chimpanzee MPZ 747431 (Entrez Gene)
Chr1 XP_009434386 (RefSeq)
cattle MPZ 539462 (Entrez Gene)
Chr3 P10522 (UniProt | EBI)
NM_001316359 (RefSeq)
dog MPZ 488654 (Entrez Gene)
Chr38 XP_545771 (RefSeq)
chicken MPZ 100859605 (Entrez Gene)
Chr25 P37301 (UniProt | EBI)
NM_001358930 (RefSeq)
zebrafish mpz 114417 (Entrez Gene)
Chr2 NP_919342 (RefSeq)
NM_194361 (RefSeq)
frog, western clawed mpz 780198 (Entrez Gene)
ChrUN A0JM41 (UniProt | EBI)
NM_001358946 (RefSeq)
macaque, rhesus MPZ 719969 (Entrez Gene)
Chr1 NP_001307984 (RefSeq)
NM_001321055 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory