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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HEXB HGNC:4879 (HGNC)
3074 (Entrez Gene)
606873 (OMIM)
HEXB (MyGene.info)
HGNC homology
Chr5 q13.3 Chr5:74640023-74721288 (+)
Sandhoff disease
P07686 (UniProt | EBI)
NM_000521 (RefSeq)
mouse Hexb MGI:96074 (MGI)
15212 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 50.66 cM Chr13:97176331-97198357 (-)
Sandhoff disease
15212 (NCBI Gene Model)
P20060 (UniProt | EBI)
NM_010422 (RefSeq)
rat Hexb 294673 (Entrez Gene)
Chr2 q12 Q6AXR4 (UniProt | EBI)
NM_001011946 (RefSeq)
chimpanzee HEXB 461807 (Entrez Gene)
Chr5 XP_009447292 (RefSeq)
cattle HEXB 618571 (Entrez Gene)
Chr20 NP_001069978 (RefSeq)
NM_001076510 (RefSeq)
LOC786974 786974 (Entrez Gene)
Chr20 XP_015323813 (RefSeq)
dog HEXB 478100 (Entrez Gene)
Chr2 XP_022270477 (RefSeq)
chicken HEXB 427204 (Entrez Gene)
ChrZ XP_424791 (RefSeq)
zebrafish hexb 323613 (Entrez Gene)
Chr5 NP_001108317 (RefSeq)
NM_001114845 (RefSeq)
frog, western clawed hexb 100145770 (Entrez Gene)
Chr1 NP_001120459 (RefSeq)
NM_001127137 (RefSeq)
macaque, rhesus HEXB 704464 (Entrez Gene)
Chr6 NP_001253386 (RefSeq)
NM_001266457 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory