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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SIX1 HGNC:10887 (HGNC)
6495 (Entrez Gene)
601205 (OMIM)
SIX1 (MyGene.info)
HGNC homology
Chr14 q23.1 Chr14:60644698-60649489 (-)
autosomal dominant nonsyndromic deafness 23
branchiootic syndrome
branchiootorenal syndrome
Q15475 (UniProt | EBI)
NM_005982 (RefSeq)
mouse Six1 MGI:102780 (MGI)
20471 (Entrez Gene)
Gene Tree
HGNC homology
Chr12 30.34 cM Chr12:73040015-73053887 (-)
branchiootorenal syndrome
OTTMUSG00000040058 (VEGA)
OTTMUSP00000058166 (VEGA)
OTTMUST00000104017 (VEGA)
rat Six1 114634 (Entrez Gene)
Chr6 q24 NP_446211 (RefSeq)
NM_053759 (RefSeq)
chimpanzee SIX1 452952 (Entrez Gene)
Chr14 XP_509988 (RefSeq)
cattle SIX1 511371 (Entrez Gene)
Chr10 XP_588692 (RefSeq)
dog SIX1 490719 (Entrez Gene)
Chr8 NP_001301061 (RefSeq)
NM_001314132 (RefSeq)
chicken SIX1 693262 (Entrez Gene)
Chr5 NP_001038150 (RefSeq)
NM_001044685 (RefSeq)
zebrafish six1b 404627 (Entrez Gene)
Chr20 Q6NZ04 (UniProt | EBI)
NM_207095 (RefSeq)
frog, western clawed six1 100101702 (Entrez Gene)
Chr8 NP_001093693 (RefSeq)
NM_001100223 (RefSeq)
macaque, rhesus SIX1 703696 (Entrez Gene)
Chr7 XP_001096585 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory