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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GDNF HGNC:4232 (HGNC)
2668 (Entrez Gene)
600837 (OMIM)
HGNC homology
Chr5 p13.2 Chr5:37812677-37840044 (-)
congenital central hypoventilation syndrome
Hirschsprung's disease
P39905 (UniProt | EBI)
NM_001190468 (RefSeq)
mouse Gdnf MGI:107430 (MGI)
14573 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 3.8 cM Chr15:7811011-7837575 (+)
Hirschsprung's disease
ENSMUSG00000022144 (Ensembl Gene Model)
ENSMUSP00000022744 (Ensembl)
ENSMUST00000022744 (Ensembl)
rat Gdnf 25453 (Entrez Gene)
Chr2 q16 Q07731 (UniProt | EBI)
NM_019139 (RefSeq)
chimpanzee GDNF 471566 (Entrez Gene)
Chr5 XP_526944 (RefSeq)
cattle GDNF 386587 (Entrez Gene)
Chr20 NP_001179778 (RefSeq)
NM_001192849 (RefSeq)
dog GDNF 489224 (Entrez Gene)
Chr4 XP_005619436 (RefSeq)
chicken GDNF 395569 (Entrez Gene)
ChrZ XP_015133018 (RefSeq)
zebrafish gdnfa 79379 (Entrez Gene)
Chr10 Q98TU0 (UniProt | EBI)
NM_131732 (RefSeq)
frog, western clawed gdnf 100498061 (Entrez Gene)
Chr1 XP_002938232 (RefSeq)
macaque, rhesus GDNF 706345 (Entrez Gene)
Chr6 XP_014995391 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory