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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
4320

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MC4R HGNC:6932 (HGNC)
4160 (Entrez Gene)
155541 (OMIM)
Chr18 q22 Chr18:60371331-60372768 (-)
GRCh38
Obesity
P32245 (UniProt | EBI)
NM_005912 (RefSeq)
mouse Mc4r MGI:99457 (MGI)
17202 (Entrez Gene)
Gene Tree
VISTA-Point
Chr18 39.72 cM Chr18:66857715-66860472 (-)
GRCm38
Fatty Liver Disease, Nonalcoholic, Susceptibility to, 1; NAFLD1
Obesity
ENSMUSG00000047259 (Ensembl Gene Model)
ENSMUSP00000054776 (Ensembl)
ENSMUST00000057942 (Ensembl)
rat Mc4r 25635 (Entrez Gene)
Chr18 q12.1 P70596 (UniProt | EBI)
NM_013099 (RefSeq)
chimpanzee MC4R 468556 (Entrez Gene)
Chr18 NP_001153207 (RefSeq)
NM_001159735 (RefSeq)
rhesus macaque MC4R 698596 (Entrez Gene)
Chr18 XP_001088600 (RefSeq)
cattle MC4R 281300 (Entrez Gene)
Chr24 Q9GLJ8 (UniProt | EBI)
NM_174110 (RefSeq)
dog MC4R 483961 (Entrez Gene)
Chr1 NP_001074193 (RefSeq)
NM_001080724 (RefSeq)
chicken MC4R 428485 (Entrez Gene)
Chr2 NP_001026685 (RefSeq)
NM_001031514 (RefSeq)
zebrafish mc4r 286833 (Entrez Gene)
Chr2 B0V1P1 (UniProt | EBI)
NM_173278 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory