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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MC4R HGNC:6932 (HGNC)
4160 (Entrez Gene)
155541 (OMIM)
Melanocortin 4 receptor (MyGene.info)
HGNC homology
Chr18 q21.32 Chr18:60371331-60372768 (-)
P32245 (UniProt | EBI)
NM_005912 (RefSeq)
mouse Mc4r MGI:99457 (MGI)
17202 (Entrez Gene)
Gene Tree
HGNC homology
Chr18 39.72 cM Chr18:66857715-66860472 (-)
fatty liver disease
ENSMUSG00000047259 (Ensembl Gene Model)
ENSMUSP00000054776 (Ensembl)
ENSMUST00000057942 (Ensembl)
rat Mc4r 25635 (Entrez Gene)
Chr18 q12.1 P70596 (UniProt | EBI)
NM_013099 (RefSeq)
chimpanzee MC4R 468556 (Entrez Gene)
Chr18 NP_001153207 (RefSeq)
NM_001159735 (RefSeq)
cattle MC4R 281300 (Entrez Gene)
Chr24 Q9GLJ8 (UniProt | EBI)
NM_174110 (RefSeq)
dog MC4R 483961 (Entrez Gene)
Chr1 NP_001074193 (RefSeq)
NM_001080724 (RefSeq)
chicken MC4R 428485 (Entrez Gene)
Chr2 NP_001026685 (RefSeq)
NM_001031514 (RefSeq)
zebrafish mc4r 286833 (Entrez Gene)
Chr2 B0V1P1 (UniProt | EBI)
NM_173278 (RefSeq)
frog, western clawed mc4r 100486677 (Entrez Gene)
Chr6 XP_004915370 (RefSeq)
macaque, rhesus MC4R 698596 (Entrez Gene)
Chr18 XP_001088600 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory