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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SMAD7 HGNC:6773 (HGNC)
4092 (Entrez Gene)
602932 (OMIM)
HGNC homology
Chr18 q21.1 Chr18:48919853-48950711 (-)
O15105 (UniProt | EBI)
NM_001190822 (RefSeq)
mouse Smad7 MGI:1100518 (MGI)
17131 (Entrez Gene)
Gene Tree
HGNC homology
Chr18 51.06 cM Chr18:75367529-75395935 (+)
ENSMUSG00000025880 (Ensembl Gene Model)
ENSMUSP00000129322 (Ensembl)
ENSMUST00000168918 (Ensembl)
rat Smad7 81516 (Entrez Gene)
Chr18 q12.2 O88406 (UniProt | EBI)
NM_030858 (RefSeq)
chimpanzee SMAD7 455411 (Entrez Gene)
Chr18 XP_016789156 (RefSeq)
cattle SMAD7 535916 (Entrez Gene)
Chr24 NP_001179794 (RefSeq)
NM_001192865 (RefSeq)
dog SMAD7 490570 (Entrez Gene)
Chr7 XP_005623188 (RefSeq)
chicken SMAD7 429683 (Entrez Gene)
ChrZ XP_427238 (RefSeq)
SMAD7B 395544 (Entrez Gene)
ChrW NP_001153135 (RefSeq)
NM_001159663 (RefSeq)
zebrafish smad7 326282 (Entrez Gene)
Chr21 NP_778257 (RefSeq)
NM_175082 (RefSeq)
frog, western clawed smad7 100486892 (Entrez Gene)
Chr1 XP_002936553 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory