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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SMAD5 HGNC:6771 (HGNC)
4090 (Entrez Gene)
603110 (OMIM)
HGNC homology
Chr5 q31.1 Chr5:136132845-136182734 (+)
Q99717 (UniProt | EBI)
NM_005903 (RefSeq)
mouse Smad5 MGI:1328787 (MGI)
17129 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 30.12 cM Chr13:56703010-56742377 (+)
ENSMUSG00000021540 (Ensembl Gene Model)
ENSMUSP00000065798 (Ensembl)
ENSMUST00000069557 (Ensembl)
rat Smad5 59328 (Entrez Gene)
Chr17 p14 Q9R1V3 (UniProt | EBI)
NM_021692 (RefSeq)
chimpanzee SMAD5 745633 (Entrez Gene)
Chr5 XP_001169580 (RefSeq)
cattle SMAD5 768050 (Entrez Gene)
Chr7 NP_001070575 (RefSeq)
NM_001077107 (RefSeq)
dog SMAD5 481520 (Entrez Gene)
Chr11 XP_538641 (RefSeq)
chicken SMAD5 395679 (Entrez Gene)
Chr13 Q56I99 (UniProt | EBI)
NM_001014968 (RefSeq)
zebrafish smad5 30641 (Entrez Gene)
Chr14 Q9W7E7 (UniProt | EBI)
NM_001346309 (RefSeq)
macaque, rhesus SMAD5 712645 (Entrez Gene)
Chr6 NP_001253244 (RefSeq)
NM_001266315 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory