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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EFS HGNC:16898 (HGNC)
10278 (Entrez Gene)
609906 (OMIM)
HGNC homology
Chr14 q11.2 Chr14:23356400-23365633 (-)
O43281 (UniProt | EBI)
NM_001277174 (RefSeq)
mouse Efs MGI:105311 (MGI)
13644 (Entrez Gene)
Gene Tree
HGNC homology
Chr14 27.99 cM Chr14:54916535-54926126 (-)
Crohn's disease
ENSMUSG00000022203 (Ensembl Gene Model)
ENSMUSP00000022813 (Ensembl)
ENSMUST00000022813 (Ensembl)
rat Efs 290212 (Entrez Gene)
Chr15 p13 NP_001099503 (RefSeq)
NM_001106033 (RefSeq)
chimpanzee EFS 452799 (Entrez Gene)
Chr14 XP_509854 (RefSeq)
cattle EFS 508559 (Entrez Gene)
Chr10 NP_001092380 (RefSeq)
NM_001098910 (RefSeq)
dog EFS 480251 (Entrez Gene)
Chr8 XP_537374 (RefSeq)
macaque, rhesus EFS 713838 (Entrez Gene)
Chr7 XP_014998892 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory