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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
4277

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ZMPSTE24 HGNC:12877 (HGNC)
10269 (Entrez Gene)
606480 (OMIM)
Chr1 p34 Chr1:40258050-40294184 (+)
GRCh38
Mandibuloacral Dysplasia with Type B Lipodystrophy; MADB
Restrictive Dermopathy, Lethal
O75844 (UniProt | EBI)
NM_005857 (RefSeq)
mouse Zmpste24 MGI:1890508 (MGI)
230709 (Entrez Gene)
Gene Tree
VISTA-Point
Chr4 56.8 cM Chr4:121059237-121098241 (-)
GRCm38
Emery-Dreifuss Muscular Dystrophy 2, Autosomal Dominant; EDMD2
Hutchinson-Gilford Progeria Syndrome; HGPS
Lipodystrophy, Familial Partial, Type 2; FPLD2
Muscular Dystrophy, Limb-Girdle, Type 1B; LGMD1B
OTTMUSG00000008909 (VEGA)
OTTMUSP00000009273 (VEGA)
OTTMUST00000020234 (VEGA)
rat Zmpste24 313564 (Entrez Gene)
Chr5 q36 NP_001101444 (RefSeq)
NM_001107974 (RefSeq)
chimpanzee ZMPSTE24 456790 (Entrez Gene)
Chr1 XP_513352 (RefSeq)
rhesus macaque ZMPSTE24 693765 (Entrez Gene)
Chr1 NP_001244375 (RefSeq)
NM_001257446 (RefSeq)
cattle ZMPSTE24 538104 (Entrez Gene)
Chr3 NP_001179857 (RefSeq)
NM_001192928 (RefSeq)
dog ZMPSTE24 482460 (Entrez Gene)
Chr15 XP_539577 (RefSeq)
chicken ZMPSTE24 419572 (Entrez Gene)
Chr23 XP_417720 (RefSeq)
zebrafish zmpste24 334380 (Entrez Gene)
Chr17 NP_956186 (RefSeq)
NM_199892 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory