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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human F2 HGNC:3535 (HGNC)
2147 (Entrez Gene)
176930 (OMIM)
HGNC homology
Chr11 p11 Chr11:46719192-46739506 (+)
Pregnancy Loss, Recurrent, Susceptibility to, 2; RPRGL2
Prothrombin Deficiency, Congenital
Stroke, Ischemic
Thrombophilia Due to Thrombin Defect; THPH1
P00734 (UniProt | EBI)
NM_000506 (RefSeq)
mouse F2 MGI:88380 (MGI)
14061 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 50.63 cM Chr2:91625329-91636407 (-)
OTTMUSG00000014282 (VEGA)
OTTMUSP00000015068 (VEGA)
OTTMUST00000033633 (VEGA)
rat F2 29251 (Entrez Gene)
Chr3 q24 P18292 (UniProt | EBI)
NM_022924 (RefSeq)
chimpanzee F2 451158 (Entrez Gene)
Chr11 XP_001165233 (RefSeq)
rhesus macaque F2 712729 (Entrez Gene)
Chr14 NP_001098055 (RefSeq)
NM_001104585 (RefSeq)
cattle F2 280685 (Entrez Gene)
Chr15 P00735 (UniProt | EBI)
NM_173877 (RefSeq)
dog F2 100856539 (Entrez Gene)
Chr18 XP_003639742 (RefSeq)
chicken F2 395306 (Entrez Gene)
Chr5 NP_989936 (RefSeq)
NM_204605 (RefSeq)
western clawed frog f2 548514 (Entrez Gene)
ChrUN NP_001015797 (RefSeq)
NM_001015797 (RefSeq)
zebrafish f2 325881 (Entrez Gene)
Chr7 NP_998555 (RefSeq)
NM_213390 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory