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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human APTX HGNC:15984 (HGNC)
54840 (Entrez Gene)
606350 (OMIM)
Aprataxin (MyGene.info)
HGNC homology
Chr9 p21.1 Chr9:32883872-33025129 (-)
ataxia with oculomotor apraxia type 1
Q7Z2E3 (UniProt | EBI)
NM_001369005 (RefSeq)
mouse Aptx MGI:1913658 (MGI)
66408 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 20.46 cM Chr4:40682382-40703194 (-)
ENSMUSG00000028411 (Ensembl Gene Model)
ENSMUSP00000124264 (Ensembl)
ENSMUST00000068125 (Ensembl)
rat Aptx 259271 (Entrez Gene)
Chr5 q22 Q8K4H4 (UniProt | EBI)
NM_148889 (RefSeq)
chimpanzee APTX 465037 (Entrez Gene)
Chr9 XP_001157209 (RefSeq)
cattle APTX 359714 (Entrez Gene)
Chr8 Q7YRZ2 (UniProt | EBI)
NM_182654 (RefSeq)
dog APTX 442943 (Entrez Gene)
Chr11 P61797 (UniProt | EBI)
NM_001003355 (RefSeq)
chicken APTX 395173 (Entrez Gene)
ChrZ P61798 (UniProt | EBI)
NM_001293074 (RefSeq)
zebrafish aptx 405797 (Entrez Gene)
Chr1 P61799 (UniProt | EBI)
NM_214729 (RefSeq)
frog, western clawed aptx 403092 (Entrez Gene)
Chr1 P61801 (UniProt | EBI)
NM_205825 (RefSeq)
macaque, rhesus APTX 702671 (Entrez Gene)
Chr15 NP_001253363 (RefSeq)
NM_001266434 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory