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HomoloGene Vertebrate Homology
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
41614

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPG11 HGNC:11226 (HGNC)
80208 (Entrez Gene)
610844 (OMIM)
HGNC homology
Chr15 q21.1 Chr15:44562696-44663678 (-)
GRCh38.p2
Charcot-Marie-Tooth Disease, Axonal, Type 2x; CMT2X
Spastic Paraplegia 11, Autosomal Recessive; SPG11
Q96JI7 (UniProt | EBI)
NM_025137 (RefSeq)
mouse Spg11 MGI:2444989 (MGI)
214585 (Entrez Gene)
Gene Tree
VISTA-Point
HGNC homology
Chr2 60.5 cM Chr2:122053520-122118386 (-)
GRCm38
Spastic Paraplegia 11, Autosomal Recessive; SPG11
OTTMUSG00000015533 (VEGA)
OTTMUSP00000016549 (VEGA)
OTTMUST00000036886 (VEGA)
rat Spg11 311372 (Entrez Gene)
Chr3 q35 NP_001178500 (RefSeq)
NM_001191571 (RefSeq)
cattle SPG11 507819 (Entrez Gene)
Chr10 XP_002691138 (RefSeq)
dog SPG11 100856719 (Entrez Gene)
Chr30 XP_013964966 (RefSeq)
chicken SPG11 415572 (Entrez Gene)
Chr10 XP_004943994 (RefSeq)
zebrafish spg11 793551 (Entrez Gene)
Chr25 NP_001181923 (RefSeq)
NM_001174135 (RefSeq)
macaque, rhesus SPG11 712221 (Entrez Gene)
Chr7 XP_014997612 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory