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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPG11 HGNC:11226 (HGNC)
80208 (Entrez Gene)
610844 (OMIM)
SPG11 (MyGene.info)
HGNC homology
Chr15 q21.1 Chr15:44562696-44663678 (-)
amyotrophic lateral sclerosis type 5
Charcot-Marie-Tooth disease axonal type 2X
hereditary spastic paraplegia 11
Q96JI7 (UniProt | EBI)
NM_025137 (RefSeq)
mouse Spg11 MGI:2444989 (MGI)
214585 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 60.5 cM Chr2:122053520-122118386 (-)
hereditary spastic paraplegia 11
OTTMUSG00000015533 (VEGA)
OTTMUSP00000016549 (VEGA)
OTTMUST00000036886 (VEGA)
rat Spg11 311372 (Entrez Gene)
Chr3 q35 NP_001178500 (RefSeq)
NM_001191571 (RefSeq)
cattle SPG11 507819 (Entrez Gene)
Chr10 XP_869859 (RefSeq)
dog SPG11 100856719 (Entrez Gene)
Chr30 XP_003640073 (RefSeq)
chicken SPG11 415572 (Entrez Gene)
Chr10 XP_004943993 (RefSeq)
zebrafish spg11 793551 (Entrez Gene)
Chr25 NP_001181923 (RefSeq)
NM_001174135 (RefSeq)
macaque, rhesus SPG11 712221 (Entrez Gene)
Chr7 XP_014997613 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory