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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TLR4 HGNC:11850 (HGNC)
7099 (Entrez Gene)
603030 (OMIM)
TLR 4 (MyGene.info)
HGNC homology
Chr9 q33.1 Chr9:117704175-117717491 (+)
age related macular degeneration 10
O00206 (UniProt | EBI)
NM_138554 (RefSeq)
mouse Tlr4 MGI:96824 (MGI)
21898 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 34.66 cM Chr4:66827584-66930284 (+)
pulmonary emphysema
OTTMUSG00000000227 (VEGA)
OTTMUSP00000000296 (VEGA)
OTTMUST00000000668 (VEGA)
rat Tlr4 29260 (Entrez Gene)
Chr5 q24 Q9QX05 (UniProt | EBI)
NM_019178 (RefSeq)
chimpanzee TLR4 743242 (Entrez Gene)
Chr9 NP_001138335 (RefSeq)
NM_001144863 (RefSeq)
cattle TLR4 281536 (Entrez Gene)
Chr8 Q9GL65 (UniProt | EBI)
NM_174198 (RefSeq)
dog TLR4 403417 (Entrez Gene)
Chr11 NP_001002950 (RefSeq)
NM_001002950 (RefSeq)
chicken TLR4 417241 (Entrez Gene)
Chr17 NP_001025864 (RefSeq)
NM_001030693 (RefSeq)
zebrafish tlr4al 795671 (Entrez Gene)
Chr13 NP_001315534 (RefSeq)
NM_001328605 (RefSeq)
tlr4ba 403131 (Entrez Gene)
Chr13 NP_001124523 (RefSeq)
NM_001131051 (RefSeq)
tlr4bb 403132 (Entrez Gene)
Chr13 NP_997978 (RefSeq)
NM_212813 (RefSeq)
macaque, rhesus TLR4 574360 (Entrez Gene)
Chr15 NP_001032169 (RefSeq)
NM_001037092 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory