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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human APRT HGNC:626 (HGNC)
353 (Entrez Gene)
102600 (OMIM)
HGNC homology
Chr16 q24.3 Chr16:88809469-88811934 (-)
adenine phosphoribosyltransferase deficiency
P07741 (UniProt | EBI)
NM_000485 (RefSeq)
mouse Aprt MGI:88061 (MGI)
11821 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 71.91 cM Chr8:122574635-122576909 (-)
adenine phosphoribosyltransferase deficiency
OTTMUSG00000061857 (VEGA)
OTTMUSP00000078282 (VEGA)
OTTMUST00000150938 (VEGA)
rat Aprt 292072 (Entrez Gene)
Chr19 q12 P36972 (UniProt | EBI)
NM_001013061 (RefSeq)
chimpanzee APRT 736305 (Entrez Gene)
Chr16 XP_003952966 (RefSeq)
cattle APRT 519017 (Entrez Gene)
Chr18 Q56JW4 (UniProt | EBI)
NM_001025334 (RefSeq)
dog APRT 479615 (Entrez Gene)
Chr5 XP_005620629 (RefSeq)
chicken APRT 100857155 (Entrez Gene)
Chr11 NP_001264579 (RefSeq)
NM_001277650 (RefSeq)
zebrafish aprt 393641 (Entrez Gene)
Chr7 NP_956962 (RefSeq)
NM_200668 (RefSeq)
frog, western clawed aprt 493317 (Entrez Gene)
Chr4 NP_001007941 (RefSeq)
NM_001007940 (RefSeq)
macaque, rhesus APRT 697715 (Entrez Gene)
Chr20 XP_014982282 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory