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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SOS1 HGNC:11187 (HGNC)
6654 (Entrez Gene)
182530 (OMIM)
SOS1 (MyGene.info)
HGNC homology
Chr2 p22.1 Chr2:38981549-39124959 (-)
gingival fibromatosis
Noonan syndrome 4
Q07889 (UniProt | EBI)
NM_005633 (RefSeq)
mouse Sos1 MGI:98354 (MGI)
20662 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 50.67 cM Chr17:80393752-80480453 (-)
Noonan syndrome 4
20662 (NCBI Gene Model)
Q62245 (UniProt | EBI)
NM_009231 (RefSeq)
rat Sos1 313845 (Entrez Gene)
Chr6 q11 NP_001094186 (RefSeq)
NM_001100716 (RefSeq)
chimpanzee SOS1 459171 (Entrez Gene)
Chr2A XP_009440628 (RefSeq)
cattle SOS1 537682 (Entrez Gene)
Chr11 XP_005212766 (RefSeq)
dog SOS1 483042 (Entrez Gene)
Chr17 XP_022260066 (RefSeq)
chicken SOS1 431192 (Entrez Gene)
Chr3 XP_003640979 (RefSeq)
frog, western clawed sos1 100489960 (Entrez Gene)
Chr5 XP_002933921 (RefSeq)
macaque, rhesus SOS1 713777 (Entrez Gene)
Chr13 XP_028687575 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory