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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
41109

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IRAK4 HGNC:17967 (HGNC)
51135 (Entrez Gene)
606883 (OMIM)
Chr12 q12 Chr12:43758944-43789543 (+)
GRCh38
Invasive Pneumococcal Disease, Recurrent Isolated, 1; IPD1
IRAK4 Deficiency
Q9NWZ3 (UniProt | EBI)
NM_016123 (RefSeq)
mouse Irak4 MGI:2182474 (MGI)
266632 (Entrez Gene)
Gene Tree
VISTA-Point
Chr15 48.55 cM Chr15:94543643-94581815 (+)
GRCm38
OTTMUSG00000016696 (VEGA)
OTTMUSP00000018065 (VEGA)
OTTMUST00000040437 (VEGA)
rat Irak4 300177 (Entrez Gene)
Chr7 q35 NP_001100261 (RefSeq)
NM_001106791 (RefSeq)
chimpanzee IRAK4 466962 (Entrez Gene)
Chr12 XP_001165893 (RefSeq)
rhesus macaque IRAK4 700568 (Entrez Gene)
Chr11 NP_001129573 (RefSeq)
NM_001136101 (RefSeq)
cattle IRAK4 533692 (Entrez Gene)
Chr5 Q1RMT8 (UniProt | EBI)
NM_001075998 (RefSeq)
dog IRAK4 486601 (Entrez Gene)
Chr27 XP_543727 (RefSeq)
chicken IRAK4 417796 (Entrez Gene)
Chr1 NP_001025909 (RefSeq)
NM_001030738 (RefSeq)
western clawed frog irak4 733738 (Entrez Gene)
ChrUN NP_001116877 (RefSeq)
NM_001123405 (RefSeq)
zebrafish irak4 393132 (Entrez Gene)
Chr25 NP_956457 (RefSeq)
NM_200163 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory