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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human REST HGNC:9966 (HGNC)
5978 (Entrez Gene)
600571 (OMIM)
HGNC homology
Chr4 q12 Chr4:56907876-56935847 (+)
autosomal dominant nonsyndromic deafness 27
gingival fibromatosis 5
Q13127 (UniProt | EBI)
NM_001193508 (RefSeq)
mouse Rest MGI:104897 (MGI)
19712 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 41.61 cM Chr5:77265494-77286432 (+)
19712 (NCBI Gene Model)
Q8VIG1 (UniProt | EBI)
NM_011263 (RefSeq)
rat Rest 83618 (Entrez Gene)
Chr14 p11 O54963 (UniProt | EBI)
NM_031788 (RefSeq)
chimpanzee REST 471235 (Entrez Gene)
Chr4 XP_009446121 (RefSeq)
cattle RESTA 615792 (Entrez Gene)
Chr6 XP_005208055 (RefSeq)
dog REST 482163 (Entrez Gene)
Chr13 XP_539282 (RefSeq)
chicken REST 422623 (Entrez Gene)
Chr4 XP_015131933 (RefSeq)
macaque, rhesus REST 100425257 (Entrez Gene)
Chr5 XP_002804152 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory