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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MRE11 HGNC:7230 (HGNC)
4361 (Entrez Gene)
600814 (OMIM)
MRE11A (MyGene.info)
HGNC homology
Chr11 q21 Chr11:94415570-94512701 (-)
P49959 (UniProt | EBI)
NM_005590 (RefSeq)
mouse Mre11a MGI:1100512 (MGI)
17535 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 4.33 cM Chr9:14784654-14837123 (+)
OTTMUSG00000031684 (VEGA)
OTTMUSP00000041737 (VEGA)
OTTMUST00000078494 (VEGA)
rat Mre11a 64046 (Entrez Gene)
Chr8 q12 Q9JIM0 (UniProt | EBI)
NM_022279 (RefSeq)
chimpanzee MRE11 737902 (Entrez Gene)
Chr11 XP_016777321 (RefSeq)
cattle MRE11 525093 (Entrez Gene)
Chr15 NP_001179534 (RefSeq)
NM_001192605 (RefSeq)
dog MRE11 494006 (Entrez Gene)
Chr21 XP_005633411 (RefSeq)
chicken MRE11 395555 (Entrez Gene)
Chr1 Q9IAM7 (UniProt | EBI)
NM_204778 (RefSeq)
zebrafish mre11a 406637 (Entrez Gene)
Chr15 NP_001307188 (RefSeq)
NM_001320259 (RefSeq)
frog, western clawed mre11 100135381 (Entrez Gene)
Chr2 NP_001107519 (RefSeq)
NM_001114047 (RefSeq)
macaque, rhesus MRE11 697566 (Entrez Gene)
Chr14 XP_014970971 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory