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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
4083

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MRE11A HGNC:7230 (HGNC)
4361 (Entrez Gene)
600814 (OMIM)
Chr11 q21 Chr11:94417300-94493874 (-)
GRCh38
Ataxia-Telangiectasia-Like Disorder 1; ATLD1
P49959 (UniProt | EBI)
NM_005590 (RefSeq)
mouse Mre11a MGI:1100512 (MGI)
17535 (Entrez Gene)
Gene Tree
VISTA-Point
Chr9 4.33 cM Chr9:14784654-14837123 (+)
GRCm38
OTTMUSG00000031684 (VEGA)
OTTMUSP00000041737 (VEGA)
OTTMUST00000078494 (VEGA)
rat Mre11a 64046 (Entrez Gene)
Chr8 q11 Q9JIM0 (UniProt | EBI)
NM_022279 (RefSeq)
chimpanzee MRE11A 737902 (Entrez Gene)
Chr11 XP_009422278 (RefSeq)
rhesus macaque MRE11A 697566 (Entrez Gene)
Chr14 XP_002799798 (RefSeq)
cattle GPR83 525093 (Entrez Gene)
Chr15 NP_001179534 (RefSeq)
NM_001192605 (RefSeq)
dog MRE11A 494006 (Entrez Gene)
Chr21 XP_542244 (RefSeq)
chicken MRE11A 395555 (Entrez Gene)
Chr1 Q9IAM7 (UniProt | EBI)
NM_204778 (RefSeq)
western clawed frog mre11a 100135381 (Entrez Gene)
ChrUN NP_001107519 (RefSeq)
NM_001114047 (RefSeq)
zebrafish mre11a 406637 (Entrez Gene)
Chr15 NP_001001407 (RefSeq)
NM_001001407 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory