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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SIRT5 HGNC:14933 (HGNC)
23408 (Entrez Gene)
604483 (OMIM)
SIRT5 (MyGene.info)
HGNC homology
Chr6 p23 Chr6:13574222-13615158 (+)
Q9NXA8 (UniProt | EBI)
NM_031244 (RefSeq)
mouse Sirt5 MGI:1915596 (MGI)
68346 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 21.6 cM Chr13:43365496-43395203 (+)
ENSMUSG00000054021 (Ensembl Gene Model)
ENSMUSP00000152526 (Ensembl)
ENSMUST00000221515 (Ensembl)
rat Sirt5 306840 (Entrez Gene)
Chr17 p12 Q68FX9 (UniProt | EBI)
NM_001004256 (RefSeq)
chimpanzee SIRT5 747069 (Entrez Gene)
Chr6 XP_003950771 (RefSeq)
cattle SIRT5 507347 (Entrez Gene)
Chr23 Q3ZBQ0 (UniProt | EBI)
NM_001034295 (RefSeq)
dog SIRT5 478726 (Entrez Gene)
Chr35 E2RDZ6 (UniProt | EBI)
NM_001313805 (RefSeq)
chicken SIRT5 420834 (Entrez Gene)
Chr2 E1BRE2 (UniProt | EBI)
NM_001276364 (RefSeq)
zebrafish sirt5 436878 (Entrez Gene)
Chr20 Q6DHI5 (UniProt | EBI)
NM_001002605 (RefSeq)
frog, western clawed sirt5 100170199 (Entrez Gene)
Chr6 F7DKV7 (UniProt | EBI)
NM_001276703 (RefSeq)
macaque, rhesus SIRT5 700855 (Entrez Gene)
Chr4 F7EZ75 (UniProt | EBI)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory