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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SMAD6 HGNC:6772 (HGNC)
4091 (Entrez Gene)
602931 (OMIM)
HGNC homology
Chr15 q22.31 Chr15:66702110-66782000 (+)
aortic valve disease 2
O43541 (UniProt | EBI)
NM_001142861 (RefSeq)
mouse Smad6 MGI:1336883 (MGI)
17130 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 34.4 cM Chr9:63953076-64022059 (-)
ENSMUSG00000036867 (Ensembl Gene Model)
ENSMUSP00000036285 (Ensembl)
ENSMUST00000041029 (Ensembl)
rat Smad6 367100 (Entrez Gene)
Chr8 q24 NP_001102472 (RefSeq)
NM_001109002 (RefSeq)
chimpanzee SMAD6 467711 (Entrez Gene)
Chr15 XP_523105 (RefSeq)
cattle SMAD6 511279 (Entrez Gene)
Chr10 NP_001193074 (RefSeq)
NM_001206145 (RefSeq)
dog SMAD6 487612 (Entrez Gene)
Chr30 XP_544737 (RefSeq)
chicken SMAD6 374096 (Entrez Gene)
Chr10 Q9W734 (UniProt | EBI)
NM_204248 (RefSeq)
zebrafish smad6b 564395 (Entrez Gene)
Chr18 NP_001038516 (RefSeq)
NM_001045051 (RefSeq)
macaque, rhesus SMAD6 714733 (Entrez Gene)
Chr7 XP_014998019 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory