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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LAMC2 HGNC:6493 (HGNC)
3918 (Entrez Gene)
150292 (OMIM)
Chr1 q25-q31 Chr1:183178827-183258333 (+)
Epidermolysis Bullosa, Junctional, Herlitz Type
Epidermolysis Bullosa, Junctional, Non-Herlitz Type
Q13753 (UniProt | EBI)
NM_005562 (RefSeq)
mouse Lamc2 MGI:99913 (MGI)
16782 (Entrez Gene)
Gene Tree
Chr1 65.26 cM Chr1:153122756-153186447 (-)
Epidermolysis Bullosa, Junctional, Herlitz Type
Epidermolysis Bullosa, Junctional, Non-Herlitz Type
OTTMUSG00000049711 (VEGA)
OTTMUSP00000068446 (VEGA)
OTTMUST00000126618 (VEGA)
rat Lamc2 192362 (Entrez Gene)
Chr13 q21 NP_001094110 (RefSeq)
NM_001100640 (RefSeq)
chimpanzee LAMC2 457571 (Entrez Gene)
Chr1 XP_009437685 (RefSeq)
rhesus macaque LAMC2 715212 (Entrez Gene)
Chr1 XP_001114169 (RefSeq)
cattle LAMC2 511043 (Entrez Gene)
Chr16 XP_588297 (RefSeq)
dog LAMC2 442939 (Entrez Gene)
Chr7 NP_001003351 (RefSeq)
NM_001003351 (RefSeq)
chicken LAMC2 408043 (Entrez Gene)
Chr8 XP_422285 (RefSeq)
western clawed frog lamc2 100489162 (Entrez Gene)
ChrUN XP_002937413 (RefSeq)
zebrafish LOC567928 567928 (Entrez Gene)
Chr2 XP_003197932 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory