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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KARS HGNC:6215 (HGNC)
3735 (Entrez Gene)
601421 (OMIM)
KARS (gene) (MyGene.info)
HGNC homology
Chr16 q23.1 Chr16:75627724-75647687 (-)
autosomal recessive nonsyndromic deafness 89
Charcot-Marie-Tooth disease recessive intermediate B
Q15046 (UniProt | EBI)
NM_005548 (RefSeq)
mouse Kars MGI:1934754 (MGI)
85305 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 58.27 cM Chr8:111993443-112011323 (-)
OTTMUSG00000061807 (VEGA)
OTTMUSP00000078216 (VEGA)
OTTMUST00000150831 (VEGA)
rat Kars 292028 (Entrez Gene)
Chr19 q12 Q5XIM7 (UniProt | EBI)
NM_001006967 (RefSeq)
chimpanzee KARS 454252 (Entrez Gene)
Chr16 XP_511115 (RefSeq)
cattle KARS 509624 (Entrez Gene)
Chr18 NP_001029528 (RefSeq)
NM_001034356 (RefSeq)
dog KARS 479644 (Entrez Gene)
Chr5 XP_022274878 (RefSeq)
chicken KARS 415885 (Entrez Gene)
Chr11 NP_001025754 (RefSeq)
NM_001030583 (RefSeq)
zebrafish kars 280647 (Entrez Gene)
Chr7 NP_001315435 (RefSeq)
NM_001002386 (RefSeq)
frog, western clawed kars 407964 (Entrez Gene)
Chr4 NP_001001255 (RefSeq)
NM_001001255 (RefSeq)
macaque, rhesus KARS 714516 (Entrez Gene)
Chr20 NP_001244522 (RefSeq)
NM_001257593 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory