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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TWIST1 HGNC:12428 (HGNC)
7291 (Entrez Gene)
601622 (OMIM)
Twist transcription factor (MyGene.info)
HGNC homology
Chr7 p21.1 Chr7:19113047-19117672 (-)
Saethre-Chotzen syndrome
Q15672 (UniProt | EBI)
NM_000474 (RefSeq)
mouse Twist1 MGI:98872 (MGI)
22160 (Entrez Gene)
Gene Tree
HGNC homology
Chr12 14.81 cM Chr12:33957671-33959829 (+)
Saethre-Chotzen syndrome
ENSMUSG00000035799 (Ensembl Gene Model)
ENSMUSP00000040089 (Ensembl)
ENSMUST00000049089 (Ensembl)
rat Twist1 85489 (Entrez Gene)
Chr6 q16 NP_445982 (RefSeq)
NM_053530 (RefSeq)
chimpanzee TWIST1 450135 (Entrez Gene)
Chr7 Q8MI03 (UniProt | EBI)
NM_001009050 (RefSeq)
chicken TWIST1 395491 (Entrez Gene)
Chr2 NP_990070 (RefSeq)
NM_204739 (RefSeq)
zebrafish LOC100535497 100535497 (Entrez Gene)
twist1a 30175 (Entrez Gene)
Chr19 NP_571059 (RefSeq)
NM_130984 (RefSeq)
twist1b 550518 (Entrez Gene)
Chr16 NP_001017820 (RefSeq)
NM_001017820 (RefSeq)
frog, western clawed twist1 395054 (Entrez Gene)
Chr6 NP_989415 (RefSeq)
NM_204084 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory