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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
402

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TWIST1 HGNC:12428 (HGNC)
7291 (Entrez Gene)
601622 (OMIM)
Chr7 p21.2 Chr7:18999692-19117672 (-)
GRCh38
Craniosynostosis 1; CRS1
Robinow-Sorauf Syndrome
Saethre-Chotzen Syndrome; SCS
Q15672 (UniProt | EBI)
NM_000474 (RefSeq)
mouse Twist1 MGI:98872 (MGI)
22160 (Entrez Gene)
Gene Tree
VISTA-Point
Chr12 14.81 cM Chr12:33957671-33959817 (+)
GRCm38
Saethre-Chotzen Syndrome; SCS
ENSMUSG00000035799 (Ensembl Gene Model)
ENSMUSP00000040089 (Ensembl)
ENSMUST00000049089 (Ensembl)
rat Twist1 85489 (Entrez Gene)
Chr6 q16 NP_445982 (RefSeq)
NM_053530 (RefSeq)
chimpanzee TWIST1 450135 (Entrez Gene)
Chr7 Q8MI03 (UniProt | EBI)
NM_001009050 (RefSeq)
chicken TWIST1 395491 (Entrez Gene)
Chr2 NP_990070 (RefSeq)
NM_204739 (RefSeq)
western clawed frog twist1 395054 (Entrez Gene)
ChrUN NP_989415 (RefSeq)
NM_204084 (RefSeq)
zebrafish LOC100535497 100535497 (Entrez Gene)
Chr16 XP_003200219 (RefSeq)
twist1a 30175 (Entrez Gene)
Chr19 NP_571059 (RefSeq)
NM_130984 (RefSeq)
twist1b 550518 (Entrez Gene)
Chr16 NP_001017820 (RefSeq)
NM_001017820 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory