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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NOG HGNC:7866 (HGNC)
9241 (Entrez Gene)
602991 (OMIM)
Noggin (protein) (MyGene.info)
HGNC homology
Chr17 q22 Chr17:56593699-56595590 (+)
brachydactyly type B2
multiple synostoses syndrome
proximal symphalangism
tarsal-carpal coalition syndrome
Q13253 (UniProt | EBI)
NM_005450 (RefSeq)
mouse Nog MGI:104327 (MGI)
18121 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 54.34 cM Chr11:89300638-89302332 (-)
esophageal atresia/tracheoesophageal fistula
OTTMUSG00000001321 (VEGA)
OTTMUSP00000001311 (VEGA)
OTTMUST00000002649 (VEGA)
rat Nog 25495 (Entrez Gene)
Chr10 q26 Q62809 (UniProt | EBI)
NM_012990 (RefSeq)
chimpanzee NOG 468413 (Entrez Gene)
Chr17 XP_523802 (RefSeq)
cattle NOG 538769 (Entrez Gene)
Chr19 XP_582573 (RefSeq)
dog NOG 100683515 (Entrez Gene)
Chr9 XP_005625045 (RefSeq)
chicken NOG 373912 (Entrez Gene)
Chr18 O93525 (UniProt | EBI)
NM_204123 (RefSeq)
zebrafish LOC100333103 100333103 (Entrez Gene)
nog1 30174 (Entrez Gene)
Chr3 Q9W741 (UniProt | EBI)
NM_130983 (RefSeq)
nog3 30173 (Entrez Gene)
Chr12 Q9YHV3 (UniProt | EBI)
NM_130982 (RefSeq)
frog, western clawed nog 493191 (Entrez Gene)
Chr10 NP_001165369 (RefSeq)
NM_001171898 (RefSeq)
macaque, rhesus NOG 707338 (Entrez Gene)
Chr16 NP_001252558 (RefSeq)
NM_001265629 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory