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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SIX3 HGNC:10889 (HGNC)
6496 (Entrez Gene)
603714 (OMIM)
SIX3 (MyGene.info)
HGNC homology
Chr2 p21 Chr2:44941898-44946077 (+)
holoprosencephaly 2
O95343 (UniProt | EBI)
NM_005413 (RefSeq)
mouse Six3 MGI:102764 (MGI)
20473 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 55.42 cM Chr17:85613608-85629302 (+)
holoprosencephaly 2
OTTMUSG00000040062 (VEGA)
OTTMUSP00000044571 (VEGA)
OTTMUST00000083049 (VEGA)
rat Six3 78974 (Entrez Gene)
Chr6 q12 NP_076480 (RefSeq)
NM_023990 (RefSeq)
chimpanzee SIX3 470367 (Entrez Gene)
Chr2A XP_016803943 (RefSeq)
cattle SIX3 616756 (Entrez Gene)
Chr11 NP_001180053 (RefSeq)
NM_001193124 (RefSeq)
dog SIX3 481356 (Entrez Gene)
Chr10 XP_538477 (RefSeq)
chicken SIX3 378786 (Entrez Gene)
Chr3 O42406 (UniProt | EBI)
NM_204364 (RefSeq)
zebrafish six3a 30635 (Entrez Gene)
Chr13 NP_571437 (RefSeq)
NM_131362 (RefSeq)
frog, western clawed six3 100493798 (Entrez Gene)
Chr5 XP_002944388 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory