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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GFRA1 HGNC:4243 (HGNC)
2674 (Entrez Gene)
601496 (OMIM)
GDNF family receptor alpha 1 (MyGene.info)
HGNC homology
Chr10 q25.3 Chr10:116056925-116273645 (-)
P56159 (UniProt | EBI)
NM_001145453 (RefSeq)
mouse Gfra1 MGI:1100842 (MGI)
14585 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 54.18 cM Chr19:58235604-58455909 (-)
Hirschsprung's disease
ENSMUSG00000025089 (Ensembl Gene Model)
ENSMUSP00000026076 (Ensembl)
ENSMUST00000026076 (Ensembl)
rat Gfra1 25454 (Entrez Gene)
Chr1 q55 Q62997 (UniProt | EBI)
NM_012959 (RefSeq)
chimpanzee GFRA1 450756 (Entrez Gene)
Chr10 XP_016774927 (RefSeq)
cattle GFRA1 534801 (Entrez Gene)
Chr26 NP_001098881 (RefSeq)
NM_001105411 (RefSeq)
dog GFRA1 609114 (Entrez Gene)
Chr28 XP_013964571 (RefSeq)
chicken GFRA1 395994 (Entrez Gene)
Chr6 O13156 (UniProt | EBI)
NM_205102 (RefSeq)
zebrafish gfra1a 79376 (Entrez Gene)
Chr13 NP_571805 (RefSeq)
NM_131730 (RefSeq)
gfra1b 79377 (Entrez Gene)
Chr12 NP_571806 (RefSeq)
NM_131731 (RefSeq)
frog, western clawed gfra1 100125202 (Entrez Gene)
Chr7 NP_001096555 (RefSeq)
NM_001103085 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory