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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MSTN HGNC:4223 (HGNC)
2660 (Entrez Gene)
601788 (OMIM)
Myostatin (MyGene.info)
HGNC homology
Chr2 q32.2 Chr2:190055700-190062729 (-)
myostatin-related muscle hypertrophy
O14793 (UniProt | EBI)
NM_005259 (RefSeq)
mouse Mstn MGI:95691 (MGI)
17700 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 26.99 cM Chr1:53061640-53068079 (+)
myostatin-related muscle hypertrophy
OTTMUSG00000046890 (VEGA)
OTTMUSP00000066957 (VEGA)
OTTMUST00000121584 (VEGA)
rat Mstn 29152 (Entrez Gene)
Chr9 q22 O35312 (UniProt | EBI)
NM_019151 (RefSeq)
chimpanzee MSTN 470605 (Entrez Gene)
Chr2B A1C2V0 (UniProt | EBI)
NM_001079919 (RefSeq)
cattle MSTN 281187 (Entrez Gene)
Chr2 q14-q15 O18836 (UniProt | EBI)
NM_001001525 (RefSeq)
dog MSTN 403433 (Entrez Gene)
Chr37 Q6UKZ8 (UniProt | EBI)
NM_001002959 (RefSeq)
chicken MSTN 373964 (Entrez Gene)
Chr7 O42220 (UniProt | EBI)
NM_001001461 (RefSeq)
zebrafish mstnb 798441 (Entrez Gene)
Chr9 O42222 (UniProt | EBI)
NM_131019 (RefSeq)
frog, western clawed mstn.1 100496408 (Entrez Gene)
Chr9 XP_002931568 (RefSeq)
macaque, rhesus MSTN 710114 (Entrez Gene)
Chr12 A1C2U6 (UniProt | EBI)
NM_001080119 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory