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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ERCC4 HGNC:3436 (HGNC)
2072 (Entrez Gene)
133520 (OMIM)
ERCC4 (MyGene.info)
HGNC homology
Chr16 p13.12 Chr16:13920138-13952348 (+)
Fanconi anemia complementation group Q
xeroderma pigmentosum group F
XFE progeroid syndrome
Q92889 (UniProt | EBI)
NM_005236 (RefSeq)
mouse Ercc4 MGI:1354163 (MGI)
50505 (Entrez Gene)
Gene Tree
HGNC homology
Chr16 8.93 cM Chr16:13109684-13150617 (+)
xeroderma pigmentosum group F
ENSMUSG00000022545 (Ensembl Gene Model)
ENSMUSP00000023206 (Ensembl)
ENSMUST00000023206 (Ensembl)
rat Ercc4 304719 (Entrez Gene)
Chr10 q11 XP_017453276 (RefSeq)
Ercc4l1 360465 (Entrez Gene)
Chr10 q11 XP_017453272 (RefSeq)
chimpanzee ERCC4 453935 (Entrez Gene)
Chr16 XP_510831 (RefSeq)
cattle ERCC4 516371 (Entrez Gene)
Chr25 NP_001192289 (RefSeq)
NM_001205360 (RefSeq)
dog ERCC4 479842 (Entrez Gene)
Chr6 XP_013970088 (RefSeq)
chicken ERCC4 416420 (Entrez Gene)
Chr14 NP_001305340 (RefSeq)
NM_001318411 (RefSeq)
zebrafish ercc4 327322 (Entrez Gene)
Chr12 NP_956079 (RefSeq)
NM_199785 (RefSeq)
frog, western clawed ercc4 100145552 (Entrez Gene)
Chr9 XP_002935520 (RefSeq)
macaque, rhesus ERCC4 712641 (Entrez Gene)
Chr20 XP_001107209 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory