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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
38289

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CHEK2 HGNC:16627 (HGNC)
11200 (Entrez Gene)
604373 (OMIM)
Chr22 q12.1 Chr22:28687743-28741834 (-)
GRCh38
Breast Cancer
Checkpoint Kinase 2, S. Pombe, Homolog Of; CHEK2
Li-Fraumeni Syndrome 2; LFS2
Osteogenic Sarcoma
Prostate Cancer
O96017 (UniProt | EBI)
NM_001005735 (RefSeq)
mouse Chek2 MGI:1355321 (MGI)
50883 (Entrez Gene)
Gene Tree
VISTA-Point
Chr5 53.73 cM Chr5:110840017-110874133 (+)
GRCm38
50883 (NCBI Gene Model)
Q9Z265 (UniProt | EBI)
NM_016681 (RefSeq)
rat Chek2 114212 (Entrez Gene)
Chr12 q16 NP_446129 (RefSeq)
NM_053677 (RefSeq)
chimpanzee CHEK2 458733 (Entrez Gene)
Chr22 XP_001172747 (RefSeq)
rhesus macaque CHEK2 713668 (Entrez Gene)
Chr10 XP_001101658 (RefSeq)
cattle CHEK2 518897 (Entrez Gene)
Chr17 NP_001029703 (RefSeq)
NM_001034531 (RefSeq)
dog CHEK2 486338 (Entrez Gene)
Chr26 XP_005636447 (RefSeq)
chicken CHEK2 768913 (Entrez Gene)
Chr15 NP_001073576 (RefSeq)
NM_001080107 (RefSeq)
zebrafish chek2 336998 (Entrez Gene)
Chr5 NP_956339 (RefSeq)
NM_200045 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory