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Vertebrate Homology Class
Class ID
HomoloGene (Release 67, Dec 12, 2012)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human YWHAE HGNC:12851 (HGNC)
7531 (Entrez Gene)
605066 (OMIM)
Chr17 p13.3 Chr17:1344540-1400375 (-)
P62258 (UniProt | EBI)
NM_006761 (RefSeq)
mouse Ywhae MGI:894689 (MGI)
22627 (Entrez Gene)
Gene Tree
Chr11 45.92 cM Chr11:75732869-75765845 (+)
Left Ventricular Noncompaction 1; LVNC1
Miller-Dieker Lissencephaly Syndrome; MDLS
OTTMUSG00000006219 (VEGA)
OTTMUSP00000006521 (VEGA)
OTTMUST00000014043 (VEGA)
rat Ywhae 29753 (Entrez Gene)
Chr10 q24 P62260 (UniProt | EBI)
NM_031603 (RefSeq)
chimpanzee LOC459638 459638 (Entrez Gene)
Chr2B XP_515815 (RefSeq)
cattle YWHAE 282125 (Entrez Gene)
Chr19 P62261 (UniProt | EBI)
NM_174491 (RefSeq)
dog YWHAE 480645 (Entrez Gene)
Chr9 XP_854358 (RefSeq)
chicken YWHAE 417554 (Entrez Gene)
Chr19 Q5ZMT0 (UniProt | EBI)
NM_001006219 (RefSeq)
zebrafish ywhae1 322060 (Entrez Gene)
Chr15 NP_997770 (RefSeq)
NM_212605 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.17
The Jackson Laboratory