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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human AP4B1 HGNC:572 (HGNC)
10717 (Entrez Gene)
607245 (OMIM)
AP4B1 (MyGene.info)
HGNC homology
Chr1 p13.2 Chr1:113894194-113905202 (-)
hereditary spastic paraplegia 47
Q9Y6B7 (UniProt | EBI)
NM_006594 (RefSeq)
mouse Ap4b1 MGI:1337130 (MGI)
67489 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 45.52 cM Chr3:103809520-103822025 (+)
ENSMUSG00000032952 (Ensembl Gene Model)
ENSMUSP00000075904 (Ensembl)
ENSMUST00000076599 (Ensembl)
rat Ap4b1 310746 (Entrez Gene)
Chr2 q34 NP_001101179 (RefSeq)
NM_001107709 (RefSeq)
chimpanzee AP4B1 457138 (Entrez Gene)
Chr1 XP_016780921 (RefSeq)
cattle AP4B1 512078 (Entrez Gene)
Chr3 NP_001095420 (RefSeq)
NM_001101950 (RefSeq)
dog AP4B1 483125 (Entrez Gene)
Chr17 XP_005630695 (RefSeq)
chicken AP4B1 419879 (Entrez Gene)
Chr26 NP_001026088 (RefSeq)
NM_001030917 (RefSeq)
zebrafish ap4b1 393309 (Entrez Gene)
Chr23 NP_956632 (RefSeq)
NM_200338 (RefSeq)
frog, western clawed ap4b1 100495149 (Entrez Gene)
Chr2 XP_002932178 (RefSeq)
macaque, rhesus AP4B1 707634 (Entrez Gene)
Chr1 XP_028686116 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory