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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CTLA4 HGNC:2505 (HGNC)
1493 (Entrez Gene)
123890 (OMIM)
HGNC homology
Chr2 q33 Chr2:203867788-203873960 (+)
Autoimmune Lymphoproliferative Syndrome, Type V; ALPS5
Celiac Disease, Susceptibility to, 3; CELIAC3
Diabetes Mellitus, Insulin-Dependent, 12; IDDM12
Hashimoto Thyroiditis
Systemic Lupus Erythematosus; SLE
P16410 (UniProt | EBI)
NM_001037631 (RefSeq)
mouse Ctla4 MGI:88556 (MGI)
12477 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 30.58 cM Chr1:60887000-60915832 (+)
OTTMUSG00000002278 (VEGA)
OTTMUSP00000002168 (VEGA)
OTTMUST00000004524 (VEGA)
rat Ctla4 63835 (Entrez Gene)
Chr9 q31 NP_113862 (RefSeq)
NM_031674 (RefSeq)
chimpanzee CTLA4 470619 (Entrez Gene)
Chr2B XP_526000 (RefSeq)
rhesus macaque CTLA4 705673 (Entrez Gene)
Chr12 NP_001038204 (RefSeq)
NM_001044739 (RefSeq)
cattle CTLA4 281732 (Entrez Gene)
Chr2 NP_776722 (RefSeq)
NM_174297 (RefSeq)
dog CTLA4 403696 (Entrez Gene)
Chr37 Q9XSI1 (UniProt | EBI)
NM_001003106 (RefSeq)
chicken CTLA4 424106 (Entrez Gene)
Chr7 NP_001035180 (RefSeq)
NM_001040091 (RefSeq)
western clawed frog ctla4 100493714 (Entrez Gene)
ChrUN XP_002936576 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory