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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ENPP1 HGNC:3356 (HGNC)
5167 (Entrez Gene)
173335 (OMIM)
HGNC homology
Chr6 q23.2 Chr6:131808016-131895155 (+)
arterial calcification of infancy
autosomal recessive hypophosphatemic rickets
type 2 diabetes mellitus
P22413 (UniProt | EBI)
NM_006208 (RefSeq)
mouse Enpp1 MGI:97370 (MGI)
18605 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 12.26 cM Chr10:24637914-24712159 (-)
arterial calcification of infancy
ossification of the posterior longitudinal ligament of spine
OTTMUSG00000019714 (VEGA)
OTTMUSP00000021308 (VEGA)
OTTMUST00000047202 (VEGA)
rat Enpp1 85496 (Entrez Gene)
Chr1 p12 Q924C3 (UniProt | EBI)
NM_053535 (RefSeq)
chimpanzee ENPP1 463002 (Entrez Gene)
Chr6 XP_016811798 (RefSeq)
cattle ENPP1 615535 (Entrez Gene)
Chr9 NP_001193141 (RefSeq)
NM_001206212 (RefSeq)
dog ENPP1 100856150 (Entrez Gene)
Chr1 XP_013975196 (RefSeq)
chicken ENPP1 426929 (Entrez Gene)
Chr3 XP_004940275 (RefSeq)
zebrafish enpp1 562399 (Entrez Gene)
Chr20 NP_001025339 (RefSeq)
NM_001030168 (RefSeq)
frog, western clawed enpp1 100422807 (Entrez Gene)
Chr5 XP_012819124 (RefSeq)
macaque, rhesus ENPP1 710140 (Entrez Gene)
Chr4 XP_001103359 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory