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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
38146

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KRT1 HGNC:6412 (HGNC)
3848 (Entrez Gene)
139350 (OMIM)
Chr12 q13.13 Chr12:52674736-52680407 (-)
GRCh38
Epidermolytic Hyperkeratosis; EHK
Ichthyosis Hystrix, Curth-Macklin Type; IHCM
Ichthyosis, Cyclic, with Epidermolytic Hyperkeratosis
Keratosis Palmoplantaris Striata III; PPKS3
Palmoplantar Keratoderma, Epidermolytic; EPPK
Palmoplantar Keratoderma, Nonepidermolytic; NEPPK
P04264 (UniProt | EBI)
NM_006121 (RefSeq)
mouse Krt1 MGI:96698 (MGI)
16678 (Entrez Gene)
Gene Tree
VISTA-Point
Chr15 57.06 cM Chr15:101845428-101850786 (-)
GRCm38
Epidermolytic Hyperkeratosis; EHK
ENSMUSG00000046834 (Ensembl Gene Model)
ENSMUSP00000023790 (Ensembl)
ENSMUST00000023790 (Ensembl)
rat Krt1 300250 (Entrez Gene)
Chr7 q36 Q6IMF3 (UniProt | EBI)
NM_001008802 (RefSeq)
chimpanzee KRT1 738375 (Entrez Gene)
Chr12 A5A6M6 (UniProt | EBI)
NM_001110818 (RefSeq)
rhesus macaque KRT1 699320 (Entrez Gene)
Chr11 XP_001098082 (RefSeq)
cattle KRT1 100301161 (Entrez Gene)
Chr5 XP_002687292 (RefSeq)
dog KRT1 444857 (Entrez Gene)
Chr27 Q6EIY9 (UniProt | EBI)
NM_001003392 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory