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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KRT1 HGNC:6412 (HGNC)
3848 (Entrez Gene)
139350 (OMIM)
Keratin 1 (MyGene.info)
HGNC homology
Chr12 q13.13 Chr12:52674736-52680407 (-)
epidermolytic hyperkeratosis
nonepidermolytic palmoplantar keratoderma
P04264 (UniProt | EBI)
NM_006121 (RefSeq)
mouse Krt1 MGI:96698 (MGI)
16678 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 57.06 cM Chr15:101845428-101850786 (-)
epidermolytic hyperkeratosis
ENSMUSG00000046834 (Ensembl Gene Model)
ENSMUSP00000023790 (Ensembl)
ENSMUST00000023790 (Ensembl)
rat Krt1 300250 (Entrez Gene)
Chr7 q36 Q6IMF3 (UniProt | EBI)
NM_001008802 (RefSeq)
chimpanzee KRT1 738375 (Entrez Gene)
Chr12 A5A6M6 (UniProt | EBI)
NM_001110818 (RefSeq)
cattle KRT1 100301161 (Entrez Gene)
Chr5 XP_003584943 (RefSeq)
dog KRT1 444857 (Entrez Gene)
Chr27 Q6EIY9 (UniProt | EBI)
NM_001003392 (RefSeq)
macaque, rhesus KRT1 699320 (Entrez Gene)
Chr11 XP_001098182 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory